oxycodone

noun

oxy·​co·​done ˌäk-sē-ˈkō-ˌdōn 

: a narcotic analgesic C₁₈H₂₁NO₄ used especially in the form of its hydrochloride

Examples of oxycodone in a Sentence

Recent Examples on the Web

This area was ground zero for funneling OxyContin and its generic equivalent, oxycodone, to virtually every state east of the Mississippi. —Sun Sentinel Editorial Board, Sun Sentinel, 2 May 2026

Authorities say fentanyl can be sold as pills with some online dealers claiming the pills are Xanax, Percocet and oxycodone. —Rosalio Ahumada, Sacbee.com, 30 Apr. 2026

Ferguson prescribed 120 milligrams of oxycodone per day to two patients — one for chronic pain and partial quadriplegia following an accident, and another for ankle and shoulder pain. —Amber Gaudet, Charlotte Observer, 27 Apr. 2026

Cook received the oxycodone supply from her mother and step-grandmother, who were both Medicaid recipients, and used the benefits to get pills. —Adam Thompson, CBS News, 23 Apr. 2026

Word History

Etymology

oxy + codeine + -one

First Known Use

1963, in the meaning defined above

Rhymes for oxycodone

• abalone
• acrimony
• alimony
• antimony
• ceremony
• chalcedony
• cicerone
• cosmogony
• eurozone
• lithopone
• macaroni
• matrimony

Medical Definition

oxycodone

noun

oxy·​co·​done -ˈkō-ˌdōn 

: a narcotic analgesic C₁₈H₂₁NO₄ used especially in the form of its hydrochloride C₁₈H₂₁NO₄·HCl to relieve moderate to severe pain

Note: Oxycodone is marketed under the trademarks OxyContin, Percocet, and Percodan.