nicotine

noun

nic·​o·​tine ˈni-kə-ˌtēn How to pronounce nicotine (audio)
: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and is used as an insecticide

Examples of nicotine in a Sentence

Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
Energy drinks and nicotine pouches help people stay alert and sharpen focus when that morning coffee caffeine jolt isn't enough. Jessica Guynn, USA Today, 28 Apr. 2026 Other factors that influence knee health include obesity and nicotine use. Stephanie Brown, Verywell Health, 27 Apr. 2026 Vapes are not subject to the ban, but laws restricting the sale of vapes and nicotine products will be strengthened under the new legislation, as will bans on smoking in public places. Adam Kovac, Scientific American, 22 Apr. 2026 The legislation that needs approval by King Charles III — a formality — before taking effect will also allow the government to regulate tobacco, vaping and nicotine products, including flavors and packaging. Los Angeles Times, 22 Apr. 2026 See All Example Sentences for nicotine

Word History

Etymology

French, from New Latin nicotiana

First Known Use

1817, in the meaning defined above

Time Traveler
The first known use of nicotine was in 1817

Cite this Entry

“Nicotine.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/nicotine. Accessed 1 May. 2026.

Kids Definition

nicotine

noun
nic·​o·​tine ˈnik-ə-ˌtēn How to pronounce nicotine (audio)
: a poisonous substance found in tobacco and used as an insecticide

Medical Definition

nicotine

noun
nic·​o·​tine ˈnik-ə-ˌtēn How to pronounce nicotine (audio)
: a poisonous alkaloid C10H14N2 that is the chief active principle of tobacco and that is used as an insecticide and is sometimes used in smoking cessation aids

Note: Trademarks for nicotine include Nicoderm, Nicorette, and Nicotrol.

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