malignant

adjective

ma·​lig·​nant mə-ˈlig-nənt How to pronounce malignant (audio)
Synonyms of malignantnext
1
: tending to produce death or deterioration
malignant malaria
especially : tending to infiltrate, metastasize, and terminate fatally
a malignant tumor
2
a
: evil in nature, influence, or effect : injurious
a powerful and malignant influence
b
: passionately and relentlessly malevolent : aggressively malicious
the malignant tongues of gossipers
c
obsolete : malcontent, disaffected
malignantly adverb

Examples of malignant in a Sentence

a highly malignant form of cancer a powerful and malignant influence
Recent Examples on the Web
Examples are automatically compiled from online sources to show current usage. Read More Opinions expressed in the examples do not represent those of Merriam-Webster or its editors. Send us feedback.
About half of mammary tumors found in dogs are benign, and of those that are malignant, most can be treated successfully with surgery if caught early enough. Samantha Agate, Kansas City Star, 28 Apr. 2026 Half of the mammary tumors found in dogs are benign, and of the malignant half, most can be treated successfully with surgery if caught early enough, the veterinary group notes. Samantha Agate, Miami Herald, 28 Apr. 2026 That one is on Stan Bowman, as was the decision to stick with Stuart Skinner and Calvin Pickard for the start of the 2025-26 season despite Skinner’s malignant inconsistency and Pickard’s career-backup resume. Sean Gentille, New York Times, 26 Apr. 2026 Giant cell tumors are typically non-cancerous, with only 4% of the tumors becoming malignant cancers, according to Cleveland Clinic. Staff Author, PEOPLE, 25 Apr. 2026 See All Example Sentences for malignant

Word History

Etymology

Late Latin malignant-, malignans, present participle of malignari

First Known Use

1542, in the meaning defined at sense 2c

Time Traveler
The first known use of malignant was in 1542

Browse Nearby Words

Cite this Entry

“Malignant.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/malignant. Accessed 1 May. 2026.

Kids Definition

malignant

adjective
ma·​lig·​nant mə-ˈlig-nənt How to pronounce malignant (audio)
1
: evil in influence or effect : injurious
2
3
: tending to produce death
malignant tumors
malignantly adverb

Medical Definition

malignant

adjective
ma·​lig·​nant mə-ˈlig-nənt How to pronounce malignant (audio)
1
: tending to produce death or deterioration
malignant malaria
especially : tending to infiltrate, metastasize, and terminate fatally
malignant tumors
compare benign sense 1
2
: of unfavorable prognosis : not responding favorably to treatment
psychotic reactions with a malignant trend

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