investigational

adjective

in·​ves·​ti·​ga·​tion·​al in-ˌve-stə-ˈgā-sh(ə-)nəl How to pronounce investigational (audio)
1
: of or relating to investigation
investigational activities
2
: relating to or being a drug or medical procedure that is not approved for general use but is under investigation in clinical trials regarding its safety and efficacy
an investigational new drug

Examples of investigational in a Sentence

Recent Examples on the Web
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Ajax’s lead asset is an investigational, once daily, oral Type II JAK2 inhibitor that’s being studied in a Phase 1 trial in patients with the rare blood cancer myelofibrosis who previously were treated with a Type 1 JAK2 inhibitor. Jeff Marks, CNBC, 27 Apr. 2026 BioAge Labs said Tuesday that its investigational pill for cardiovascular risk prevention significantly reduced inflammation in an early study, as more drug companies target inflammation as a way to treat a range of chronic conditions. Elaine Chen, STAT, 21 Apr. 2026 The film shows Dane's desire for the reauthorization of the ACT for ALS, a 2021 law which grants funding to scientific research and expands access to investigational ALS treatments for people who are not otherwise eligible for clinical trials. Anthony Robledo, USA Today, 10 Apr. 2026 Clinical study recap The Langenhops enrolled in a clinical trial testing an investigational therapy developed by Rocket Pharmaceuticals. Kerry Breen, CBS News, 27 Mar. 2026 See All Example Sentences for investigational

Word History

First Known Use

1905, in the meaning defined at sense 1

Time Traveler
The first known use of investigational was in 1905

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Cite this Entry

“Investigational.” Merriam-Webster.com Dictionary, Merriam-Webster, https://www.merriam-webster.com/dictionary/investigational. Accessed 2 May. 2026.

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