genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism compare proteome

Examples of genome in a Sentence

Recent Examples on the Web

Notably, Venter used his own genome as his sample for the effort. —Claire Cameron, Scientific American, 30 Apr. 2026

But getting genomes into cells is not trivial. —Eliza Strickland, IEEE Spectrum, 30 Apr. 2026

The genes for the 21 proteins in the small subunit are all clustered next to each other on a 10,000-base-long stretch of the genome, so the researchers could just replace them all at once. —ArsTechnica, 30 Apr. 2026

Venter led the effort to produce one of the first draft sequences of the human genome. —Francie Ebert, NBC news, 30 Apr. 2026

Word History

Etymology

German Genom, from Gen gene + -om (as in Chromosom chromosome)

First Known Use

1926, in the meaning defined above

Phrases Containing genome

• genome editing

Rhymes for genome

• biome
• megohm
• nichrome
• noisome
• prodrome
• radome
• rhizome
• shalom
• syndrome
• acrosome
• aerodrome
• catacomb

Medical Definition

genome

noun

ge·​nome ˈjē-ˌnōm 

: one haploid set of chromosomes with the genes they contain

broadly : the genetic material of an organism

The idea behind sequencing an organism's genome—decoding, letter by letter, the message contained in every last one of its genes—is that it would tell us a lot about how the organism works.

—Lori Oliwenstein, Discover