creatine

noun

cre·​a·​tine ˈkrē-ə-ˌtēn 

-tᵊn

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in the muscles of vertebrates either free or as phosphocreatine

also : a synthetic usually hydrated form of creatine taken especially as a dietary supplement

Examples of creatine in a Sentence

Recent Examples on the Web

Combining electrolytes with creatine may support hydration status, especially during prolonged or intense exercise. —Morgan Pearson, Verywell Health, 15 Apr. 2026

Beyond the natural production of the amino acid, about half the body's supply of creatine comes from the foods one eats. —Daryl Austin, USA Today, 12 Apr. 2026

Goldin credited Create Wellness’s approachable lifestyle branding with accelerating trial and adoption of creatine beyond the traditional gym-bro crowd. —Emma Sandler, Forbes.com, 30 Mar. 2026

Some data suggest that multivitamins, vitamin D, and omega-3 or fish oil supplements can help fill nutrient gaps while taking GLP-1s, and that protein and creatine supplementation may help preserve lean mass and build muscle strength during weight loss. —Lauren Manaker, SELF, 10 Mar. 2026

Word History

Etymology

French créatine, from Greek kreat-, kreas flesh — more at raw

First Known Use

1840, in the meaning defined above

Phrases Containing creatine

• creatine kinase
• creatine phosphate

Rhymes for creatine

• aten
• clayton
• satan
• statin
• straighten

Medical Definition

creatine

noun

cre·​atine ˈkrē-ə-ˌtēn, -ət-ᵊn 

: a white crystalline nitrogenous substance C₄H₉N₃O₂ found especially in vertebrate muscle either free or as phosphocreatine